Reference-Based vs De Novo Assembly: Choosing the Right Approach
Genome assembly can be tackled in two main ways: aligning reads to a reference genome, or building an assembly from scratch (de novo). Both strategies are po...
Posts by Category
Informative
Short Reads vs Long Reads: What’s the Difference and Why It Matters
Not all sequencing technologies are created equal. If you’ve ever wondered why some people swear by Illumina and others rave about Oxford Nanopore or PacBio,...
Terminally Chill: Getting Comfortable with the Command Line
The command line can feel intimidating when you’re new. But trust me, it doesn’t have to be. In fact, getting comfortable with the terminal is one of the bes...
Conda? Mamba? Docker? Figuring Out Package Management Without Losing Your Mind
Ever tried installing a tool, only to break your entire setup in the process due to conflicting dependencies? Luckily, you don’t need to suffer. Let’s talk a...
So You Wanna Do Bioinformatics?
Thinking of diving into bioinformatics but not sure if your laptop is up to the task? You’re not alone. Let’s talk about what kind of setup you actually need...
Tutorial
Mapping with Confidence: A Beginner’s Guide to Reference-Based Assembly
When you have a good reference genome, reference-based assembly is often the most efficient way to make sense of your sequencing data. In this post, we’ll wa...